ALG6 : ALG6 alpha-1,3-glucosyltransferase
Description
The ALG6 (ALG6 alpha-1,3-glucosyltransferase) is a protein-coding gene located on chromosome 1.
The ALG6 gene provides instructions for making an enzyme involved in glycosylation, a process where sugar molecules (oligosaccharides) are attached to proteins and fats. Oligosaccharides are complex chains made up of many sugar molecules linked together. Glycosylation modifies proteins, enabling them to perform a wider range of functions. The enzyme produced by the ALG6 gene transfers a simple sugar called glucose to the growing oligosaccharide. Once the correct number of sugar molecules are linked, the oligosaccharide is attached to a protein or fat.
Adds the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Man(9)GlcNAc(2)-PP-Dol.
ALG6 is also known as CDG1C.
