CDSN
Description
The CDSN (corneodesmosin) is a protein-coding gene located on chromosome 6.
Corneodesmosin is a protein that in humans is encoded by the CDSN gene. This gene encodes a protein found in corneodesmosomes, which localize to the human epidermis and other cornified squamous epithelia. During maturation of the cornified layers, the protein undergoes a series of cleavages, which are thought to be required for desquamation. The gene is located in the major histocompatibility complex (MHC) class I region on chromosome 6.
Plays a crucial role in maintaining the structural integrity of the epidermal barrier.
CDSN is also known as HTSS, HTSS1, HYPT2, PSS, PSS1.
