FLG : filaggrin
Description
The FLG gene, provides instructions for making filaggrin, a protein crucial for skin barrier function. Filaggrin helps bind together keratin fibers, forming a protective layer that prevents moisture loss and protects against external irritants. Mutations in the FLG gene can disrupt this process, leading to a weakened skin barrier and increased susceptibility to various skin conditions.
Associated Diseases
- Atopic Dermatitis (Eczema)
- Ichthyosis Vulgaris
- Asthma
- Allergic Rhinitis
- Food Allergies
- Psoriasis
- Skin Infections
Did you know?
People with mutations in the FLG gene have a higher risk of developing atopic dermatitis, a common skin condition characterized by itchy, red, and dry skin.
