APOBEC3F
Description
APOBEC3F is a gene that encodes a cytidine deaminase enzyme involved in the innate immune response. It plays a critical role in defending against retroviruses, including HIV, by introducing mutations into viral DNA, rendering it non-functional. APOBEC3F also contributes to DNA damage and mutagenesis in cancer cells, potentially acting as a tumor suppressor.
Associated Diseases
Did you know?
APOBEC3F activity can be hijacked by some viruses, like HIV, which evolve to evade its antiviral effects.
