Bacteroides fragilis
Bacteroides fragilis: A Versatile Gut Resident
Description
Bacteroides fragilis is a Gram-negative, anaerobic bacterium that is a common resident of the human gut microbiome. It is one of the most abundant bacterial species in the human gut, accounting for up to 20% of the total microbial population. B. fragilis plays a crucial role in gut health by fermenting complex carbohydrates, producing short-chain fatty acids (SCFAs), and maintaining immune homeostasis.
Associated Diseases
While B. fragilis is generally considered a beneficial bacteria, it has been implicated in the development of certain diseases, including:
- Inflammatory bowel disease (IBD): Studies have shown that individuals with IBD have lower levels of B. fragilis in their gut microbiome.
- Colorectal cancer: Some research suggests that an imbalance of B. fragilis in the gut may increase the risk of colorectal cancer.
- Bacteremia: B. fragilis can occasionally enter the bloodstream and cause bacteremia, a life-threatening infection.
Did you Know ?
- B. fragilis is the most abundant bacterial species in the human gut microbiome after the age of 65.
