BRMS1L
Description
The BRMS1L (BRMS1 like transcriptional repressor) is a protein-coding gene located on chromosome 14.
BRMS1L plays a role in suppressing gene expression by interacting with HDAC1, a histone deacetylase. In lung cancer cells lacking the p53 tumor suppressor gene, overexpressing BRMS1L can slow down cell growth.
BRMS1L is also known as BRMS1, p40.
Associated Diseases
- cancer
- major depressive disorder
- melorheostosis with osteopoikilosis
- dacryocystitis-osteopoikilosis syndrome
- melorheostosis
- 12q14 microdeletion syndrome
- breast cancer
- pyknoachondrogenesis
- osteomesopyknosis
- gnathodiaphyseal dysplasia
