BTNL8
Description
The BTNL8 (butyrophilin like 8) is a protein-coding gene located on chromosome 5.
BTNL8 may contribute to the initiation of immune responses by activating T cells. It interacts with the TCR/CD3 complex on T cells, but less effectively than optimal stimulation, leading to increased T cell proliferation and cytokine production.
BTNL8 is also known as BTN9.2.
Associated Diseases
- colorectal cancer
- major depressive disorder
- cancer
- congenital T-cell immunodeficiency
- achalasia-alacrima syndrome
