C2CD5
Description
The C2CD5 (C2 calcium dependent domain containing 5) is a protein-coding gene located on chromosome 12.
C2CD5 plays a crucial role in insulin-stimulated glucose uptake by facilitating the movement of glucose transporter 4 (GLUT4) from intracellular storage vesicles to the cell surface in fat cells (adipocytes). This protein interacts with cell membranes in a calcium-dependent manner and is essential for efficient fusion between the vesicles containing GLUT4 and the cell membrane.
C2CD5 is also known as CDP138, KIAA0528.
Associated Diseases
- tuberculosis
- substance abuse
- LIPE-related familial partial lipodystrophy
- PLIN1-related familial partial lipodystrophy
- CIDEC-related familial partial lipodystrophy
- obesity due to melanocortin 4 receptor deficiency
