CCNB3
Description
The CCNB3 (cyclin B3) is a protein-coding gene located on chromosome X.
CCNB3, a cyclin protein, is a key regulator of cell cycle progression, particularly during the G2 phase and mitosis. Cyclins act as positive regulators of cyclin-dependent kinases (CDKs), controlling cell cycle events. Notably, CCNB3's breakdown during cell division is essential for proper cycle control. The specific expression pattern of CCNB3 suggests it plays a crucial role in the early stages of meiotic prophase I.
CCNB3 is also known as CYCB3.
Associated Diseases
- male infertility with teratozoospermia due to single gene mutation
- spermatogenic failure 61
- spermatogenic failure 73
- spermatogenic failure 74
- spermatogenic failure 20
- spermatogenic failure 48
- spermatogenic failures 50
- spermatogenic failure 5
- spermatogenic failure 31
- spermatogenic failure 26
- spermatogenic failure 25
- spermatogenic failure 1
- spermatogenic failure 72
- spermatogenic failure 18
- spermatogenic failure 27
- spermatogenic failure 46
- spermatogenic failure 43
