CD109
Description
The CD109 (CD109 molecule) is a protein-coding gene located on chromosome 6.
CD109 (Cluster of Differentiation 109) is a human gene that encodes a GPI-linked cell surface antigen. It is found on the surface of various cell types, including CD34+ acute myeloid leukemia cell lines, T-cell lines, activated T lymphoblasts, endothelial cells, and activated platelets. CD109 is also responsible for the platelet-specific Gov antigen system (HPA15), which is involved in complications like refractoriness to platelet transfusion, neonatal alloimmune thrombocytopenia, and posttransfusion purpura.
Inhibits the signaling of the transforming growth factor beta 1 (TGFB1) pathway in keratinocytes.
CD109 is also known as CPAMD7, p180, r150.
