CDKL2
Description
The CDKL2 (cyclin dependent kinase like 2) is a protein-coding gene located on chromosome 4.
CDKL2 gene encodes for an enzyme called Cyclin-dependent kinase-like 2, which is a member of a large family of CDC2-related serine/threonine protein kinases. It is mainly found in the cytoplasm with lower levels in the nucleus.
CDKL2 is also known as KKIAMRE, P56.
Associated Diseases
- type 2 diabetes mellitus
- nonpapillary renal cell carcinoma
- autosomal recessive hypophosphatemic rickets
- hypoparathyroidism, familial isolated, 2
- pentosuria
- autosomal dominant hypophosphatemic rickets
- pseudohypoparathyroidism type 2
- cancer
