CKS2
Description
The CKS2 (CDC28 protein kinase regulatory subunit 2) is a protein-coding gene located on chromosome 9.
The CKS2 gene in humans encodes the Cyclin-dependent kinases regulatory subunit 2 protein. This protein binds to the catalytic subunit of cyclin-dependent kinases and is essential for their activity. The CKS2 mRNA expression varies throughout the cell cycle in HeLa cells, suggesting a specialized role for the protein. You can find more information about the CKS2 gene and its location on the UCSC Genome Browser.
CKS2 binds to the catalytic subunit of cyclin-dependent kinases, playing a crucial role in their function.
CKS2 is also known as CKSHS2.
Associated Diseases
- cancer
- breast cancer
- male infertility with teratozoospermia due to single gene mutation
- female infertility due to oocyte meiotic arrest
- female infertility due to zona pellucida defect
- partial chromosome Y deletion
- oocyte maturation defect 9
- premature ovarian failure 19
