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The COMMD6 (COMM domain containing 6) is a protein-coding gene located on chromosome 13.
COMMD6 might regulate the activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. It downregulates the activation of NF-kappa-B and inhibits TNF-induced NFKB1 activation.
COMMD6 is also known as Acrg.
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