CROT
Description
The CROT (carnitine O-octanoyltransferase) is a protein-coding gene located on chromosome 7.
CROT is a human gene that encodes a protein involved in fatty acid metabolism.
CROT is involved in the beta-oxidation of fatty acids, particularly those with chain lengths between C6 and C10. It converts 4,8-dimethylnonanoyl-CoA, the final product of pristanic acid beta oxidation, into its corresponding carnitine ester.
CROT is also known as COT.
Associated Diseases
- ringed hair disease
- Griscelli syndrome type 3
- uncombable hair syndrome
- microcephaly-albinism-digital anomalies syndrome
- pili bifurcati
- oculocutaneous albinism type 3
- alopecia, androgenetic, 1
- wooly hair, autosomal recessive 3
- Tietz syndrome
- ermine phenotype
- hypotrichosis simplex
- Waardenburg syndrome, IIa 2F
