CSAD
Description
The CSAD (cysteine sulfinic acid decarboxylase) is a protein-coding gene located on chromosome 12.
CSAD catalyzes the removal of a carboxyl group (CO2) from several amino acids: L-aspartate, 3-sulfino-L-alanine (cysteine sulfinic acid), and L-cysteate. This process produces beta-alanine, hypotaurine, and taurine, respectively. CSAD has a strong preference for 3-sulfino-L-alanine as a substrate. However, it does not demonstrate any activity towards glutamate.
CSAD is also known as CSD, PCAP.
Associated Diseases
- Parkinson disease
- lysosomal storage disease
- Alzheimer disease
- multiple sclerosis
- type 1 diabetes mellitus
- hypertension, pregnancy-induced
- toxemia of pregnancy
- familial primary pulmonary hypoplasia
- pyknoachondrogenesis
- type 2 diabetes mellitus
