CXXC4
Description
The CXXC4 (CXXC finger protein 4) is a protein-coding gene located on chromosome 4.
CXXC4 is a gene that encodes a protein involved in regulating the Wnt signaling pathway. This pathway is essential for cell development and growth, and CXXC4 appears to act as a negative regulator. CXXC4 preferentially binds to DNA sequences containing CpG dinucleotides, hinting at its role in gene expression and DNA methylation.
CXXC4 acts as a negative regulator of the Wnt signaling pathway by interacting with DVL1. It exhibits preferential binding to DNA sequences containing CpG dinucleotides compared to CpH (H = A, T, or C), hemimethylated-CpG, and hemimethylated-hydroxymethyl-CpG. This binding preference suggests a role in regulating gene expression and DNA methylation.
CXXC4 is also known as IDAX.
