DACT3
Description
The DACT3 (dishevelled binding antagonist of beta catenin 3) is a protein-coding gene located on chromosome 19.
DACT3 is thought to be involved in regulating intracellular signaling pathways during development, particularly the canonical and/or non-canonical Wnt signaling pathways. It accomplishes this by interacting with the Dishevelled (DSH) family proteins.
DACT3 is also known as DAPPER3, RRR1.
Associated Diseases
- diabetes mellitus, permanent neonatal 4
- permanent neonatal diabetes mellitus 1
- congenital lethal erythroderma
- nephronophthisis
- nephronophthisis 1
- nephronophthisis 3
- hyperlipoproteinemia type V
- familial juvenile hyperuricemic nephropathy type 2
- colorectal cancer
