IFT74
Description
The IFT74 gene provides instructions for making a protein that plays a crucial role in the assembly and function of cilia, microscopic hair-like structures found on the surface of many cells. These cilia are involved in a wide range of cellular processes, including sensory perception, fluid movement, and cell signaling. Mutations in IFT74 can disrupt ciliary function, leading to a variety of human diseases.
Associated Diseases
- Bardet-Biedl syndrome (BBS)
- Joubert syndrome (JS)
- Sensenbrenner syndrome
- Orofaciodigital syndrome type I (OFD1)
- Nephronophthisis (NPH)
- Meckel-Gruber syndrome (MKS)
- Senior-Loken syndrome (SLS)
- Alstrom syndrome (ALMS)
Did you know?
IFT74 is a highly conserved gene, meaning its sequence is very similar across different species, highlighting its essential role in cellular function.
