L2HGDH : L-2-hydroxyglutarate dehydrogenase
Description
The L2HGDH (L-2-hydroxyglutarate dehydrogenase) is a protein-coding gene located on chromosome 14.
The L2HGDH gene provides instructions for making an enzyme called L-2-hydroxyglutarate dehydrogenase. This enzyme is found in mitochondria, which are the energy-producing centers within cells. Within mitochondria, the enzyme participates in reactions that produce energy for cell activities. Specifically, L-2-hydroxyglutarate dehydrogenase converts a compound called L-2-hydroxyglutarate to another compound called 2-ketoglutarate. A series of additional enzymes further process 2-ketoglutarate to produce energy.
L2HGDH encodes an enzyme that plays a crucial role in mitochondrial energy production. This enzyme, L-2-hydroxyglutarate dehydrogenase, converts L-2-hydroxyglutarate into 2-ketoglutarate, a compound further processed by other enzymes to generate energy for cellular activities.
L2HGDH is also known as C14orf160, L2HGA.
