MTOR
The MTOR gene, also known as mechanistic target of rapamycin, plays a crucial role in cellular signaling.
Associated Diseases
Focal cortical dysplasia type II, Smith-Kingsmore syndrome, Cancer
Did you know
mTOR is aberrantly overactivated in more than 70% of human cancers.
Additonal info
The MTOR gene, also known as mechanistic target of rapamycin, plays a crucial role in cellular signaling. It forms two distinct protein complexes: TOR complex-1 (TORC1), which regulates cell growth and mRNA translation, and TOR complex-2 (TORC2), which promotes actin cytoskeletal rearrangement, cell survival, and cell cycle progression.
