ODAD4

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Description

The ODAD4 (outer dynein arm docking complex subunit 4) is a protein-coding gene located on chromosome 17.

ODAD4 is a subunit of the outer dynein arm-docking complex (ODA-DC). It plays a crucial role in anchoring the outer dynein arms (ODA) to the doublet microtubules in the ciliary axoneme. This anchoring process is essential for the assembly of the ODA-DC and the proper function of cilia.

ODAD4 is also known as TTC25.

Associated Diseases

• Ciliary dyskinesia, primary, 35
• Primary ciliary dyskinesia