HMGN2

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Description

The HMGN2 (high mobility group nucleosomal binding domain 2) is a protein-coding gene located on chromosome 1.

HMGN2 is a gene that encodes the non-histone chromosomal protein HMG-17.

HMGN2 binds to the inner side of nucleosomal DNA, modifying the interaction between DNA and the histone octamer. This suggests a role in maintaining the unique chromatin structure of transcribable genes.

HMGN2 is also known as HMG17.

Associated Diseases

• type 2 diabetes mellitus