IAPP
Description
The IAPP (islet amyloid polypeptide) is a protein-coding gene located on chromosome 12.
IAPP, or Islet Amyloid Polypeptide, is a protein produced by the pancreatic beta-cell. It is linked to type II diabetes. IAPP can also refer to other things, including an Inter-Access Point Protocol, an iOS application, and several organizations.
IAPP selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle tissue, while not affecting glucose metabolism in fat cells (adipocytes).
IAPP is also known as DAP, IAP.
Associated Diseases
- AL amyloidosis
- type 2 diabetes mellitus
- progressive supranuclear palsy
- Gorham-Stout disease
- type 1 diabetes mellitus
- nail-patella syndrome
- Kallmann syndrome
- acroosteolysis
- familial avascular necrosis of femoral head
