IDI2

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Description

The IDI2 (isopentenyl-diphosphate delta isomerase 2) is a protein-coding gene located on chromosome 10.

IDI2 catalyzes the rearrangement of isopentenyl diphosphate (IPP) into its isomer, dimethylallyl diphosphate (DMAPP). This reaction involves a 1,3-allylic shift, converting a homoallylic substrate into a highly electrophilic allylic isomer.

IDI2 is also known as IPPI2.

Associated Diseases

• breast cancer
• Treacher-Collins syndrome
• COVID-19
• hyperinsulinemic hypoglycemia, familial, 4
• cancer