INSL6
Title: INSULIN-LIKE GROWTH FACTOR 6 (INSL6)
Description:
Insulin-like growth factor 6 (INSL6) is a protein hormone that belongs to the insulin superfamily. It is primarily produced by Leydig cells in the testes and is involved in regulating fertility and reproductive development.
Associated Diseases:
Mutations in the INSL6 gene are associated with several disorders, including:
- Cryptorchidism (undescended testes)
- Leydig cell aplasia (absence of Leydig cells)
- Kallmann syndrome (a rare genetic disorder characterized by delayed puberty and infertility)
Did you Know ?
Approximately 1 in 500 men worldwide are affected by cryptorchidism, which is often associated with INSL6 mutations.
