JAZF1
Description
The JAZF1 (JAZF zinc finger 1) is a protein-coding gene located on chromosome 7.
JAZF1, also known as TAK1-interacting protein 27 (TIP27) or zinc finger protein 802 (ZNF802), is a protein encoded by the JAZF1 gene in humans. It is a nuclear protein with three C2H2-type zinc fingers and functions as a transcriptional repressor. Variants in this gene are associated with an increased risk of prostate cancer, an increased risk of type 2 diabetes, and an increased height. Chromosomal aberrations involving JAZF1 are associated with endometrial stromal tumors.
JAZF1 is also known as TIP27, ZNF802.
