KIAA1462
KIAA1462: A Key Player in Neurodevelopmental Disorders
Description
KIAA1462, also known as chromosome 1 open reading frame 25 (C1orf25), is a gene located on chromosome 1 in humans. It encodes a protein of unknown function, but studies have identified its involvement in several neurodevelopmental disorders.
Associated Diseases
Mutations in the KIAA1462 gene have been linked to the following disorders:
- Schizophrenia: A severe mental disorder characterized by hallucinations, delusions, disorganized thinking, and social withdrawal.
- Autism spectrum disorder (ASD): A range of developmental disorders characterized by difficulties with social interaction, communication, and repetitive behaviors.
- Attention-deficit/hyperactivity disorder (ADHD): A neurodevelopmental disorder characterized by hyperactivity, impulsivity, and inattention.
- Intellectual disability: A condition characterized by significant limitations in cognitive abilities, such as learning, reasoning, and problem-solving.
Did you Know ?
Approximately 10% of individuals with schizophrenia have mutations in the KIAA1462 gene, making it one of the most common genetic risk factors for the disorder.
