KRT32
Description
The KRT32 (keratin 32) is a protein-coding gene located on chromosome 17.
Keratin, type I cuticular Ha2 is a protein that in humans is encoded by the KRT32 gene. The protein encoded by this gene is a member of the keratin gene family. As a type I hair keratin, it is an acidic protein which heterodimerizes with type II hair keratin to form hair and nails. The type I hair keratins are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription.
KRT32 is also known as HA2, HKA2, KRTHA2, hHa2.
Associated Diseases
- ovarian cancer
- thyroid gland adenocarcinoma
- esophageal cancer
- hemoglobin E-beta-thalassemia syndrome
- hemoglobin D disease
- cholesterol-ester transfer protein deficiency
- hypertriglyceridemia 2
- dominant beta-thalassemia
- hemoglobin E disease
- delta-beta-thalassemia
- hemoglobin C-beta-thalassemia syndrome
- alpha-thalassemia-myelodysplastic syndrome
- homozygous familial hypercholesterolemia
- sitosterolemia
- hemoglobin H disease
- thyroid hormone metabolism, abnormal, 2
