LOC113230
Loc113230: An Emerging Clinical Target for Precision Medicine
Description
Loc113230, also known as the long non-coding RNA (lncRNA) MIR4435-2HG, is a gene located on chromosome 11q13.2. It is a non-coding RNA molecule that does not encode proteins but plays a crucial role in regulating gene expression.
Associated Diseases
Research has linked loc113230 to various diseases, including:
- Cancer: Dysregulated expression of loc113230 has been observed in several cancers, such as colorectal cancer, breast cancer, and lung cancer. It is believed to promote tumor growth and metastasis.
- Cardiovascular diseases: Alterations in loc113230 expression have been associated with coronary artery disease and heart failure.
- Neurological disorders: Studies suggest that loc113230 may contribute to neurodegenerative diseases like Alzheimer's and Parkinson's disease.
- Metabolic disorders: Dysregulation of loc113230 has been linked to obesity and type 2 diabetes.
Did you Know ?
In a study of patients with colorectal cancer, researchers found that elevated levels of loc113230 were associated with a significantly worse prognosis. Patients with high loc113230 expression had a 40% lower survival rate than those with low expression.
