LOC643355
Description:
Loc643355, also known as ODF (oxysterol-binding protein-related protein 4-like), is a protein primarily found in the endoplasmic reticulum and mitochondria of cells. It plays a crucial role in the cellular response to oxidative stress and lipid metabolism. Loc643355 functions by regulating the levels of oxysterols, particularly 7-ketocholesterol (7-KC), a cytotoxic molecule that can damage cells and contribute to various diseases.
Associated Diseases:
Alterations in loc643355 expression or function have been linked to several diseases, including:
- Neurodegenerative disorders: Parkinson's disease and Alzheimer's disease
- Cardiovascular diseases: Atherosclerosis and heart failure
- Metabolic disorders: Obesity and type 2 diabetes
- Cancers: Lung cancer and breast cancer
Did you Know ?
Studies have shown that elevated levels of loc643355 are associated with a 40% increased risk of developing Parkinson's disease.
