NCKAP5L

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Description

The NCKAP5L (NCK associated protein 5 like) is a protein-coding gene located on chromosome 12.

NCKAP5L regulates microtubule organization and stabilization. It promotes microtubule growth and bundling formation. NCKAP5L stabilizes microtubules by increasing intense acetylation of microtubules. Tubulin-binding and homodimer formation are both required for NCKAP5L-mediated microtubule bundle formation.

NCKAP5L is also known as Cep169, FP1193, KIAA1602.

Associated Diseases

• cancer
• type 2 diabetes mellitus