NCS1
Description
The NCS1 (neuronal calcium sensor 1) is a protein-coding gene located on chromosome 9.
NCS1 or NCS1 may refer to:
NCS1, also known as neuronal calcium sensor 1, is a calcium-dependent regulator of G protein-coupled receptor phosphorylation. It directly regulates GRK1 but not other GRKs (GRK2-GRK5). NCS1 can substitute for calmodulin and stimulates PI4KB kinase activity. It participates in long-term synaptic plasticity by interacting with PICK1 and may also contribute to neuron differentiation by inhibiting N-type voltage-gated calcium channels.
NCS1 is also known as FLUP, FREQ.
Associated Diseases
- cancer
- snowflake vitreoretinal degeneration
- megalocornea
- macular corneal dystrophy
- Parkinson disease
- lattice corneal dystrophy type I
- autosomal dominant keratitis
- X-linked endothelial corneal dystrophy
- congenital primary aphakia
- Norrie disease
- Stickler syndrome type 2
