NUBP2
Description
The NUBP2 (NUBP iron-sulfur cluster assembly factor 2, cytosolic) is a protein-coding gene located on chromosome 16.
Nucleotide-binding protein 2 (NBP 2), also known as cytosolic Fe-S cluster assembly factor NUBP2, is a protein that in humans is encoded by the NUBP2 gene. NUBP2 is a member of the NUBP/MRP gene subfamily of ATP-binding proteins. There are two types in eukaryotes NUBP1 and NUBP2, and one novel human gene that define NBP nucleotide-binding proteins (NUBP/MRP-multidrug resistance-associated protein) in mammalian cells requires the maturation of cytosolic iron-sulfur (Fe/S) proteins as Nubp1 is involved in the formation of extramitochondrial Fe/S proteins the cell division inhibitor MinD is homologous and involve two proteins components of the (FeS) protein assembly machinery closely similar cytosolic soluble P loop NTPase where Nar1 is required for assembly, identified Cfd1p in cytosolic and nuclear Fe/S protein biogenesis in yeast. Nubp proteins NTPase Nbp35p. MinD is homologous to members in MinD of E. coli, a relative of the ParA family.
== Morphology == Further information: Morphology (biology) NBP35 bacterial plasmids F (the classical Escherichia coli sex factor) is found in all nuclear genes in vegetative and gametic flagella of the unicellular green algae C. reinhardtii and nuclear Fe/S protein biogenesis required for cytosolic iron-sulfur protein assembly; MNP =MRP-like; MRP (Multiple Resistance and pH adaptation) MRP/NBP35-like P-loop NTPase similar to; and functions as minD_arch; cell division ATPase MinD, archaeal and homologue's of NUBP1. The NBP35 gene is conserved in archaea Bacteria, Metazoa, Fungi and other Eukaryotes and with considerable divergence from the yeast; Cfd1-Nbp35 Fe-S to man. In a scaffold complex protein to form large molecular assemblies that store Fe(III) and 4Fe-4S seen as secondary to defects inactivated to accomplish its functions as physiologically relevant form(s) Fe/S proteins Iron regulatory protein 1 (IRP1) is regulated through prevents deficiencies and increased mutation rates that characterized a plant P loop NTPase with sequence similarity to Nbp35 homologue's of NUBP1.
== Interactions == NUBP2 has been shown to interact with...
NUBP2 is also known as CFD1, CIAO6, NBP 2, NUBP1.
Associated Diseases
- Gollop-Wolfgang complex
- tibia, hypoplasia or aplasia of, with polydactyly
- Blount disease
- acheiropody
- syndactyly type 4
- acromesomelic dysplasia 2C, Hunter-Thompson type
