OR2C1
Description
The OR2C1 (olfactory receptor family 2 subfamily C member 1) is a protein-coding gene located on chromosome 16.
OR2C1 is a protein encoded by the human OR2C1 gene. It belongs to a large family of G-protein-coupled receptors (GPCRs) involved in smell perception. OR2C1 interacts with odorant molecules in the nose, initiating a neuronal response that leads to the perception of a smell. The olfactory receptor gene family is the largest in the human genome. OR2C1, like other olfactory receptors, has a 7-transmembrane domain structure and is responsible for recognizing and transducing odorant signals through G protein-mediated pathways.
OR2C1 is activated by binding to organosulfur odorants containing thioether groups, such as (methylthio)methanetiol (MTMT). It also binds odorants acetophenone and benzaldehyde. OR2C1's activity is mediated by G proteins, which in turn activate adenylyl cyclase. OR2C1 may play a role in the molecular processes underlying fasciculation and targeting of olfactory axons.
OR2C1 is also known as OLFmf3, OR2C2P.
