OSTF1
Description
The OSTF1 (osteoclast stimulating factor 1) is a protein-coding gene located on chromosome 9.
Osteoclast-stimulating factor 1 is a protein produced by the OSTF1 gene in humans.
OSTF1 promotes bone resorption. It likely works through a chain of signals that lead to the release of substances that encourage osteoclast formation and activity.
OSTF1 is also known as OSF, SH3P2, bA235O14.1.
Associated Diseases
- X-linked retinal dysplasia
- Gorham-Stout disease
- melorheostosis
- retinitis pigmentosa
- dacryocystitis-osteopoikilosis syndrome
- 12q14 microdeletion syndrome
- pyknoachondrogenesis
- microphthalmia with limb anomalies
- osteosclerosis-ichthyosis-premature ovarian failure syndrome
- osteomesopyknosis
- severe early-childhood-onset retinal dystrophy
- reticular dystrophy of the retinal pigment epithelium
- hyperostosis corticalis generalisata
