PDCL
Description
The PDCL (phosducin like) is a protein-coding gene located on chromosome 9.
Phosducin-like protein is a protein that in humans is encoded by the PDCL gene. Phosducin-like protein is a putative modulator of heterotrimeric G proteins. The protein shares extensive amino acid sequence homology with phosducin, a phosphoprotein expressed in the retina and pineal gland. Both phosducin-like protein and phosphoducin have been shown to regulate G-protein signaling by binding to the beta-gamma subunits of G proteins.
PDCL is also known as PhLP.
Associated Diseases
- esophageal cancer
- retinal degeneration
- cryopyrin-associated periodic syndrome
- cancer
- situs inversus
- allergic disease
