TUBE1
Description
The TUBE1 (tubulin epsilon 1) is a protein-coding gene located on chromosome 6.
The TUBE1 gene in humans encodes Tubulin, epsilon 1, a protein belonging to the tubulin superfamily. This protein is localized to the centriolar sub-distal appendages, which are associated with the older of the two centrioles after centrosome duplication.
TUBE1 is also known as TUBE, dJ142L7.2.
Associated Diseases
- schizophrenia 15
- Phelan-McDermid syndrome
- FRAXE intellectual disability
- Potocki-Lupski syndrome
- Smith-Magenis syndrome
- intellectual developmental disorder, X-linked, syndromic, Pilorge type
- intellectual developmental disorder with epilepsy, behavioral abnormalities, and coarse facies
- colorectal cancer
- cancer
