DEGS2

• SHARE NOW |
• Tweet Opens in a new window.
• Pin it Opens in a new window.
• Share Opens in a new window.
• Share Opens in a new window.
• Email Opens in a new window.

---

Description

The DEGS2 (delta 4-desaturase, sphingolipid 2) is a protein-coding gene located on chromosome 14.

DEGS2 is a gene that encodes a protein involved in the biosynthesis of sphingolipids, primarily in human skin and other tissues containing phytosphingolipids. This enzyme has two functions: it can act as a sphingolipid delta(4)-desaturase and also as a sphingolipid C4-hydroxylase.

DEGS2 acts as both a sphingolipid delta(4)-desaturase and a sphingolipid C4-monooxygenase.

DEGS2 is also known as C14orf66, DES2, FADS8.

Associated Diseases

• cancer
• schizophrenia