DGAT2L6
Description
The DGAT2L6 (diacylglycerol O-acyltransferase 2 like 6) is a protein-coding gene located on chromosome X.
DGAT2L6 is a diglyceride acyltransferase that uses fatty acyl-CoA as a substrate, particularly active with oleate as a substrate. It does not have wax synthase activity to produce wax esters. It can also utilize 1-monoalkylglycerol (1-MAkG) as an acyl acceptor to synthesize monoalkyl-monoacylglycerol (MAMAG).
DGAT2L6 is also known as DC3.
Associated Diseases
- prostate cancer
- isolated asymptomatic elevation of creatine phosphokinase
- pentosuria
- myopathy due to calsequestrin and SERCA1 protein overload
- metabolic myopathy due to lactate transporter defect
