DNASE2B
Description
The DNASE2B (deoxyribonuclease 2 beta) is a protein-coding gene located on chromosome 1.
DNASE2B, also known as DNase II-like acid DNase, hydrolyzes DNA under acidic conditions without requiring divalent cations for activity. It plays a role in the degradation of nuclear DNA during lens cell differentiation.
DNASE2B is also known as DLAD.
Associated Diseases
- granular corneal dystrophy type II
- early-onset non-syndromic cataract
- cataract
- cataract 12 multiple types
- aniridia
- cataract 8 multiple types
- gelatinous drop-like corneal dystrophy
- retinitis pigmentosa
- pulverulent cataract
- achromatopsia
- isolated ectopia lentis
- X-linked corneal dermoid
- Leber congenital amaurosis
- hemoglobin D disease
- familial pterygium of the conjunctiva
