DNPEP
Description
The DNPEP (aspartyl aminopeptidase) is a protein-coding gene located on chromosome 2.
Aspartyl aminopeptidase is an enzyme produced by the human DNPEP gene. This enzyme preferentially cleaves acidic amino acids, particularly aspartic acid, from the N-terminus of proteins. It is thought to be localized within cells and participates in the general metabolism of intracellular proteins.
Aspartyl aminopeptidase is an enzyme that shows a preference for acidic amino acids, particularly aspartic acid, at the N-terminus of proteins and peptides. It is believed to be involved in the breakdown of intracellular proteins and peptides, playing a role in general intracellular protein metabolism.
DNPEP is also known as ASPEP, DAP.
Associated Diseases
- multiple sclerosis
- Parkinson disease
- lysosomal storage disease
- Alzheimer disease
- thrombocytopenia 4
- macrothrombocytopenia, isolated, 2, autosomal dominant
- platelet-type bleeding disorder 15
- autosomal dominant macrothrombocytopenia
- platelet-type bleeding disorder 10
- thrombocytopenia 2
- bleeding disorder, platelet-type, 24
- DIAPH1-related sensorineural hearing loss-thrombocytopenia syndrome
- autosomal dominant nonsyndromic hearing loss 1
- beta-thalassemia-X-linked thrombocytopenia syndrome
