DPPA5

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Description

The DPPA5 (developmental pluripotency associated 5) is a protein-coding gene located on chromosome 6.

DPPA5 plays a role in maintaining the pluripotency of embryonic stem (ES) cells. While not essential for the self-renewal of pluripotent ES cells or the development of germ cells, it associates with specific target messenger RNA molecules.

DPPA5 is also known as ESG1.

Associated Diseases

• Hirschsprung disease
• proximal spinal muscular atrophy