ECT2L
Description
The ECT2L (epithelial cell transforming 2 like) is a protein-coding gene located on chromosome 6.
ECT2L is a protein encoded by the ECT2L gene in humans. Recurrent mutations in this gene have been linked to cases of acute lymphoblastic leukemia.
May act as a guanine nucleotide exchange factor (GEF).
ECT2L is also known as ARHGEF32, C6orf91, FBXO49, LFDH, dJ509I19.2, dJ509I19.3, dJ509I19.5.
Associated Diseases
- urinary bladder carcinoma
- skin squamous cell carcinoma
- superficial spreading melanoma
- central nervous system primitive neuroectodermal neoplasm
- carcinoma of liver and intrahepatic biliary tract
