EVPL
Description
The EVPL (envoplakin) is a protein-coding gene located on chromosome 17.
EVPL is a human gene.
EVPL is a component of the cornified envelope, the outermost layer of skin cells. It may connect the cornified envelope to desmosomes, which are cell-to-cell junctions, and intermediate filaments, which are protein fibers that provide structural support.
EVPL is also known as EVPK.
Associated Diseases
- thyroid gland adenocarcinoma
- ovarian cancer
- esophageal cancer
- urinary bladder cancer
- low grade glioma
- endometrial cancer
- focal palmoplantar and gingival keratoderma
- hereditary palmoplantar keratoderma, Gamborg-Nielsen type
- hyperkeratosis lenticularis perstans
- ichthyosis histrix, Lambert type
- focal palmoplantar keratoderma
- reticulate acropigmentation of Kitamura
- palmoplantar keratoderma-deafness syndrome
