FBXO21

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Description

The FBXO21 (F-box protein 21) is a protein-coding gene located on chromosome 12.

FBXO21 is a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.

FBXO21 is also known as FBX21.

Associated Diseases

• schizophrenia
• type 2 diabetes mellitus
• X-linked endothelial corneal dystrophy
• microphthalmia with limb anomalies
• granular corneal dystrophy type I
• lattice corneal dystrophy type I