FBXO30
Description
The FBXO30 (F-box protein 30) is a protein-coding gene located on chromosome 6.
FBXO30 acts as a substrate recognition component within the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex. This complex plays a crucial role in muscle atrophy, specifically after denervation, indicating FBXO30's involvement in muscle breakdown.
FBXO30 is also known as Fbx30.
Associated Diseases
- dermatophytosis
- nonpapillary renal cell carcinoma
- cancer
- autosomal dominant Emery-Dreifuss muscular dystrophy
