RSPH4A
Description
The RSPH4A (radial spoke head component 4A) is a protein-coding gene located on chromosome 6.
RSPH4A, also known as radial spoke head-like protein 3, is a protein encoded by the RSPH4A gene in humans. It is a component of the radial spoke head, a structure found in cilia and flagella, which are hair-like structures that play a role in movement and sensory function. The radial spoke head acts as a signal transduction scaffold, connecting the central pair of microtubules to the dynein motor proteins that drive ciliary movement. Mutations in the RSPH4A gene are associated with primary ciliary dyskinesia, a condition that affects the function of cilia and can lead to respiratory problems, infertility, and other health issues.
RSPH4A is also known as CILD11, RSHL3, RSPH6B, dJ412I7.1.
