SP7

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Description

The SP7 (Sp7 transcription factor) is a protein-coding gene located on chromosome 12.

SP7 may refer to:

SP7 is a transcriptional activator that plays a crucial role in osteoblast differentiation. It binds to specific DNA sequences, including those recognized by SP1 and EKLF, as well as other G/C-rich sequences.

SP7 is also known as OI11, OI12, OSX, osterix.

Associated Diseases

• Craniodiaphyseal dysplasia
• Osteogenesis imperfecta, type XII