SPTB
Description
The SPTB (spectrin beta, erythrocytic) is a protein-coding gene located on chromosome 14.
The SPTB gene in humans codes for the protein spectrin beta chain, erythrocyte.
Spectrin is a key component of the erythrocyte cytoskeleton, forming a network beneath the plasma membrane. It interacts with proteins like band 4.1 and actin to create a structural framework that supports the erythrocyte membrane.
SPTB is also known as EL3, HS2, HSPTB1, SPH2.
