TKFC
Description
The TKFC (triokinase and FMN cyclase) is a protein-coding gene located on chromosome 11.
TKFC catalyzes the phosphorylation of both dihydroxyacetone and glyceraldehyde, and also splits ribonucleoside diphosphate-X compounds, with FAD being the most effective substrate. This protein suppresses the cellular antiviral response mediated by IFIH1.
TKFC is also known as DAK, NET45, TKFCD.
Associated Diseases
- Congenital cataract-hypertrophic cardiomyopathy-mitochondrial myopathy syndrome
- Triokinase and FMN cyclase deficiency syndrome
